Elysium Health, Inc.™, a leading life sciences company developing clinically validated health products based on advancements in ageing research, has announced the launch of FORMAT™, the first and only immune product to uniquely pair a daily immunomodulatory supplement with an intermittent senolytic complex to combat the effects of immune ageing and provide complete immune support.
Format’s daily immunomodulatory supplement combines micronutrients critical at every stage of the immune response; a Free Radical Protection Complex containing antioxidants including sulforaphane and elderberry; and an Autophagy Activation Complex including bioavailable green tea phytosomes and chalcone flavonoids. The formulation of Format’s Senolytic Complex is based on leading institutional research in the field of cellular senescence and was developed under the advisement of an expert member of Elysium Health’s renowned Scientific Advisory Board. It contains a powerful blend of proven senolytic compounds, including quercetin and fisetin, to help the body manage senescent cells, support healthy immune function, and combat immunosenescence.
“At Elysium Health, we develop novel products with the world’s best scientists and institutions at the forefront of ageing research to help people lead healthier lives,” said Eric Marcotulli, chief executive officer of Elysium Health. “As a company focused on ageing research, addressing age-related decline in immune function has been part of our product pipeline for several years. Format is the first and only product to address immune ageing by uniquely combining a daily immune supplement to support healthy immune function with an intermittent senolytic complex to help the body manage senescent cells and combat inflammaging and immunosenescence.”
Immunosenescence, which broadly describes age-related decline of the immune system, is a natural part of the ageing process that occurs universally, even in healthy adults. One potential cause of this age-related decline is the accumulation of senescent cells—cells that stop dividing but remain metabolically active. The accumulation of senescent cells places a burden on the immune system, contributes to inflammation, and has been associated with numerous health concerns. Recent research has also shown that senescent immune cells have the ability to accelerate systemic ageing. In people of any age, the immune system can be quickly compromised as a result of various lifestyle factors, including lack of sleep, a diet poor in fruits and vegetables and high in fat, anxiety and chronic stress, smoking, and excessive alcohol consumption—according to the National Institutes of Health, drinking to excess on even a single occasion slows your body’s ability to ward off infections for up to 24 hours.
“Format is unique in combining a daily immunomodulatory cocktail with intermittent, proven senolytic compounds to clear senescent cells,” said Dr. Leonard Guarente, chief scientist at Elysium Health and director of the Glenn Center for Biology of Aging Research at MIT. “It is a safe way to provide multi-pronged immune support that is not available in any other health supplement. Indeed, a recent preclinical study by Yousefzadeh et al. published in Nature demonstrated that senescent hematopoietic cells can play a critical role in ageing and health decline.”