DuPont Nutrition & Health Confirms Appetite-Reducing Ability of Dietary Fibre

Leading journals publish meta-analyses of Litesse® polydextrose effects


Kantvik, Finland – DuPont Nutrition & Health has collated convincing scientific evidence to support the appetite-suppressing effect of the dietary fiber Litesse® polydextrose, part of the DuPont™ Danisco® range, in two meta-analyses. Both have now been published in scientific journals.

The meta-analyses are the outcome of a systematic review of key studies that have investigated the impact of Litesse® consumption on calorie intake and subjective feelings of appetite.


Calorie consumption reduced by 5-15 per cent

Summarising the studies of calorie intake, the first meta-analysis concludes that the inclusion of 6.25-25g of Litesse® in a mid-morning snack reduces lunchtime calorie consumption by 5-15 per cent.“In addition, we have seen that this reduction in calorie intake is not compensated for during the rest of the day and may play a role in reducing total daily calorie intake significantly,” says Dr. Alvin Ibarra, senior scientist and member of the DuPont Nutrition & Health review team.


Impact on appetite

The meta-analysis of subjective appetite ratings found a similar positive effect of Litesse® polydextrose.

Dr. Ibarra said: “This shows that Litesse® is able to reduce the desire to eat immediately after a meal, which includes Litesse®. There is also a trend towards reduced hunger and increased satisfaction between meals after the consumption of Litesse®”. And he goes on to say: “This means that Litesse® represents a very exciting opportunity for our customers who wish to develop their weight management products with satiety-enhancing and appetite-reduction qualities. Our customer applying Litesse® to their own brands can now help consumers reduce their caloric consumption and help them meet their weight-management goals.”


A new methodology for measuring changes in appetite

During the review of the studies of appetite ratings, the biggest challenge was to make a meaningful comparison of results obtained from widely differing criteria. The DuPont scientific team met the challenge head on by developing a new methodology for estimating changes in appetite before and after a meal.

Dr. Ibarra adds: “We are now using this new methodology to analyse the appetite rating results during the satiation and satiety periods with a positive acceptance from the scientific community.”


Publication in key journals

The meta-analyses of calorie intake and subjective feelings of appetite have been published in the peer-reviewed journal Appetite and a special Food and Appetite issue of Nutrients. The references are as follows:

Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K. Effects of Polydextrose on Different Levels of Energy Intake: A Systematic Review and Meta-Analysis. Appetite. 2015 Apr 1;87C:30-37.

Ibarra A, Astbury NM, Olli K, Alhoniemi E, Tiihonen K. Effect of Polydextrose on Subjective Feelings of Appetite during the Satiation and Satiety Periods. A Systematic Review and Meta-Analysis. Nutrients. 2016.